What is ribose?
 Who needs Ribocor?
 How is ribose made in the body?
 How does the body derive cellular energy from ribose?
 How does taking Ribocor aid in increasing cellular energy?
 What will Ribocor do for someone concerned about cardiovascular health?
 What is the recommended daily dosage of Ribocor?
 Are there any side effects associated with taking Ribocor?
 What will Ribocor do for someone who exercises on a regular basis?
 Does Ribocor work with creatine or other supplements?
 Why is the use of Ribocor on the rise?

What is ribose?
D-ribose is a simple, 5-carbon monosaccharide, or pentose sugar. It is used by all the cells of the body and is an essential compound in energy metabolism. Ribose is also the carbohydrate backbone of genetic material, DNA and RNA, certain vitamins and other important cellular compounds. Ribocor is D ribose.

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Who needs Ribocor?
Every cardiac patient needs Ribocor. It is an essential ingredient in stimulating natural energy production. Research has shown that Ribocor promotes cardiovascular health, reduces cardiac stress associated with strenuous activity and helps athletes reach new heights. Ribocor helps hearts and muscles maximize energy recovery. Whether you are a trained athlete, a weekend warrior or are concerned about your cardiovascular health, Ribocor may help give the energy boost your body needs.

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How is ribose made in the body?
All the necessary compounds for life are made in the body through a series of complicated biochemical metabolic pathways. Ribose is no different. In the body, ribose is made from glucose (a simple 6-carbon sugar) through a pathway called the Pentose Phosphate Pathway (PPP) or Hexose Monophosphate Shunt (HMS). Unfortunately, in heart and muscle cells important enzymes that regulate the activity of this pathway are lacking. As such, forming ribose in heart and muscle cells is a slow process. As a result heart and muscle tissues are unable to replace energy pools quickly once they have been depleted by disease or exercise.

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How does the body derive cellular energy from ribose?
The physiologically functional form of ribose, called 5-phosphoribosyl-1-pyrophosphate (PRPP), regulates the metabolic pathway that synthesizes energy compounds in all living tissue. If this compound is not available in sufficient quantity, energy synthesis slows.

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How does taking Ribocor aid in increasing cellular energy?
If the cellular energy pool is depleted by disease or exercise it must be replaced. PRPP is required to turn on the metabolic pathway used by the body to replenish these energy pools. Ribocor bypasses the slow and rate limiting Pentose Phosphate Pathway, forms PRPP, and quickly begins the process of energy synthesis.

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What will Ribocor do for someone concerned about cardiovascular health?
Numerous medical studies have shown that energy levels in the heart can be dramatically lowered by exercise or decreased blood flow associated with certain cardiac diseases. Depleted cardiac energy pools may be associated with increased cardiac stress, reduced blood flow to the periphery of the body, fatigue and decreased exercise tolerance. Ribocor is the key nutrient for quickly restoring cardiac energy pool.

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What is the recommended daily dosage of Ribocor?
For energy enhancement, 2 - 5 grams is generally adequate. Ribocor is mildly sweet and completely soluble. It mixes easily with your favorite juice, milk or other cold foods. To maximize athletic performance, or to keep energy pools high during strenuous activity, slightly larger doses may be required. Ribocor should be taken just before and just after exercise or activity. For extended exercise, an additional 1 - 2 grams per hour of exercise or activity may be helpful.

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Are there any side effects associated with taking Ribocor?
Ribocor should be taken in doses up to 5 grams at a time. Multiple 5-gram doses separated by 30 - 45 minutes can be taken without side effects. There are two known side effects of taking ribose in doses of 10 grams or more on an empty stomach. The first is a transient hypoglycemia (low blood sugar) that can be eliminated by taking larger doses of ribose with other carbohydrates (such as in juice). The second side effect that may occur in some individuals is loose stools. Again, this side effect has only been reported in very large doses, greater than 10 grams. Total daily intake of ribose should be limited to 20 grams, or approximately 4 rounded teaspoonfuls.

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What will Ribocor do for someone who exercises on a regular basis?
Scientific research shows that three or four workouts per week may not allow enough rest time between sessions for heart and muscle energy pools to return to normal levels. Taking Ribocor shortens the time needed by heart and muscle tissue to replace energy that is lost through vigorous exercise. Keeping energy pools full helps to keep hearts and muscles in good physiological condition, increase power and endurance, and reduce fatigue. Recent research has also shown that ribose supplementation during exercise reduces free radical formation and lowers cardiac stress associated with hypoxia.

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Does Ribocor work with creatine or other supplements?
Ribocor can increase the effect of creatine and other energy supplements by keeping the energy pool at full capacity. Creatine works by recycling energy that is already present in the tissue. Another supplement, carnitine, aids in fatty acid metabolism. A third, pyruvate, also helps to recycle energy. None of these other supplements, however, help to maintain the pool of energy in the cell. Only ribose performs this important metabolic function. Without adequate levels of energy to work with, no other supplement can be fully effective.

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Why is the use of Ribocor on the rise?
Traditionally, ribose has been very expensive to produce making it difficult to offer as a nutritional supplement. New technology has brought production costs down. In addition, ribose is safe and proven effective by many clinical and laboratory studies. Over 70 scientific publications describe the beneficial effects of ribose in hearts and muscles.

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